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Simvastatin
Clinical data
Pronunciation/ ˈ s ɪ m v ə s t æ t ɪ n /
Trade namesZocor, other
AHFS/Drugs.comMonograph
MedlinePlusa692030
License dataEU  EMA:  by INN, US   FDA: Simvastatin
Pregnancy categoryAU: D US: X (Contraindicated)
Routes of administrationby mouth
ATC codeC10AA01 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) UK: P (Pharmacy medicines) when ≤10 mg/day, POM when >10 mg/day., US: ℞-only
Pharmacokinetic data
Bioavailability5%
Protein binding95%
MetabolismHepatic (CYP3A4)
Elimination half-life2 hours for simvastatin and 1.9 hours for simvastatin acid
ExcretionRenal 13%, faecal 60%

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Simvastatin info
Tablet name Simvastatin
Simvastatin all other nameactalipid, docsimvasta, doctiverine, dosavastatin, lipex, lipinorm, lodales, normotherin, simbastatin, simcard, simgal, simvastatina, simvastatinum, simvofix, simvor, sinvacor, sivastin, statinal, vasilip, zeid, zocord, zorced, zorstat, zosta, zostin, zostine, zovast, zovastin, zovatin, zurocid
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Ng h/ml to 43. +/- 16.It is not known whether simvastatin is excreted into price of simvastatin at walmart milk; however, a small amount of another drug in this class does pass into breast milk. Because statins have the potential for serious adverse reactions in nursing infants, women who require treatment with simvastatin should not breastfeed their infants The risk of myopathy, including rhabdomyolysis, is dose related.

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It should be noted that although 10 mg once daily is an FDA-labeled dosage of simvastatin, this dosage was not evaluated in randomized controlled studies reviewed by the ACC/AHA expert panel."Cardiovascular disease: risk assessment and reduction, including lipid modification at ice.

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